Associate Professor
B.S. (Louisiana State University, USA, 2002)
Ph.D. (University of Texas, Austin, USA, 2010)
Postdoc (University of Illinois, Urbana-Champaign, USA, 2011-2016)
Office: Otto Maass 222
Phone: (514) 398-3637
Lab: P&P 312
Email: Christopher.Thibodeaux [at] 大发彩票平台.ca
奥别产辫补驳别:听
Research Themes
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Biological Chemistry
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Analytical Chemistry
Research Description
Our research applies a diverse set of experimental tools spanning the realms of biochemistry, analytical chemistry, biophysics, molecular biology, and bioinformatics to study the biosynthesis of antimicrobial natural products, the biological processes that contribute to bacterial virulence, and the role of protein conformational dynamics in enzymes of biomedical relevance to humans.
Correlating Structure with Function in Enzymes of Biomedical Relevance
Broadly, we are interested in understanding the mechanisms of natural product biosynthetic enzymes and in understanding the role of protein conformational changes and structural dynamics in enzyme function. Many of our projects focus on enzymes that make antimicrobial compounds, that contribute to bacterial virulence/pathogenesis, or that have other biomedically-relevant functions. In general, the enzymes we study also rely on conformational changes to facilitate substrate recognition, signal with other enzymes, mediate allosteric activation, or to define the kinetic and catalytic properties of the enzyme. Our research employs a range of methodologies that provide trainees with a diverse experimental tool kit for careers in academia, private industry, or medicine. This includes expertise in molecular biology, biochemistry, microbiology, bioinformatics, analytical chemistry, quantitative analysis and data fitting, as well as biophysics and structural modelling. In particular, we have strong interests in the application of emerging mass spectrometry-based techniques and other biophysical approaches to correlate enzyme structural dynamics with biochemical functions.
Currently Teaching
CHEM 367. Instrumental Analysis 1.
Note: For information about Fall 2025 and Winter 2026 course offerings, please check back on May 8, 2025. Until then, the "Terms offered" field will appear blank for most courses while the class schedule is being finalized.
Credits: 3
Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
An introduction to modern instrumental analysis emphasizing chromatography, atomic spectroscopy and computational data analysis. Analytical methods to be examined in detail include gas-liquid and high performance liquid chromatography, LC mass spectrometry, and common methods of atomic determinations using flames/furnaces/plasma sources.
- Each lab section is limited enrolment
- Fall
- Prerequisite(s): CHEM 267.
- Each lab section is limited enrolment
Most students use Visual Schedule Builder (VSB) to organize their schedules. VSB helps you plan class schedules, travel time, and more.
CHEM 502. Advanced Bio-Organic Chemistry.
Note: For information about Fall 2025 and Winter 2026 course offerings, please check back on May 8, 2025. Until then, the "Terms offered" field will appear blank for most courses while the class schedule is being finalized.
Credits: 3
Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.
- Restriction: Not open to students who have taken CHEM 402.
- Winter
- Prerequisite: CHEM 302
- Restriction: Not open to students who have taken CHEM 402.
Most students use Visual Schedule Builder (VSB) to organize their schedules. VSB helps you plan class schedules, travel time, and more.
CHEM 520. Methods in Chemical Biology.
Note: For information about Fall 2025 and Winter 2026 course offerings, please check back on May 8, 2025. Until then, the "Terms offered" field will appear blank for most courses while the class schedule is being finalized.
Credits: 3
Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
An overview of advanced techniques at the leading edge of Chemical Biology, including some or all of: biological imaging, kinetics of enzyme inhibition, combinatorial synthesis, atomic force microscopy of biological molecules, self assembling biomimetic structures, oligonucleotide therapeutics, biomolecular X-ray crystallography, computational methods, and nuclear magnetic resonance applied to protein interactions.
- Fall
- Prerequisites: BIOL 200 and CHEM 345 and CHEM 302, or permission of instructor
Most students use Visual Schedule Builder (VSB) to organize their schedules. VSB helps you plan class schedules, travel time, and more.
