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A HoLDI mass spectrometry platform for airborne nanoplastic detection
Published: 25 March 2025
路 There are no established protocols for nanoplastic detection within complex environmental matrices.
路 Mass spectrometry (MS) analysis of environmental nanoplastics is impeded by methodological constraints.
路 Ariya's lab, namely Zi Wang, present a versatile platform evolved from matrix-assisted laser desorption/ionization (MALDI) MS for airborne nano/microplastic research.
路 The 3D-printed hollow-laser desorption/ionization (HoLDI) target enables efficient, high-throughput analysis of aerosols collected on simple substrates without pre/post-treatments.
路 HoLDI-MS determines the chemical composition and relative quantity of real-world airborne nano/microplastics, while used with conventional portable samplers and particle analyzers.
路 Polyethylene, polyethylene glycol, and polydimethylsiloxanes are detected in an indoor environment, with a higher amount in the micro-sized range.
路 Polycyclic aromatic hydrocarbons present in an outdoor setting, with a higher quantity in the nano-sized range. Morphological and elemental data provide additional evidence for observed contaminants and support multidisciplinary research interests.
路 HoLDI holds promise as a standardized analytical framework for any air or water samples, facilitating research harmonization worldwide.
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